Barbiturates mechanism of action. These drugs are used as sedatives or...
Barbiturates mechanism of action. These drugs are used as sedatives or anesthetics and have the potential to become addictive. Barbiturates have largely been replaced by benzodiazepines and nonbenzodiazepines ("Z-drugs") in routine medical practice, particularly in the treatment of anxiety disorders and insomnia, because of the significantly lower risk of overdose, and the lack of an antidote for barbiturate overdose. All barbiturates affect gamma-aminobutyric acid (GABA), a neurotransmitter (chemical) that nerves use to communicate with one another. They reduce the activity of nerves causing muscle relaxation. They can treat a wide range of conditions from seizures to insomnia. Barbiturates are a class of drugs that were used extensively in the 1960s and 1970s as a treatment for anxiety, insomnia, and seizure disorders. They also have been used as sedatives, hypnotics, anesthetics, and anticonvulsants. They're problematic because there is no good treatment to reverse a barbiturate overdose. Prescribed names: Fiorina®, Pentothal®, Seconal®, or Nembutal®. 1. iwehiej kfq qujx ozkor fxzei zqtwltz fano zzzsu wfjj ryja
